What is the difference between compiling typescripts in label and compiling typescripts in tsc?

You can compile typescript using plugin in the label, but what is the difference from compiling using tsc?

Even if js and ts are mixed, if you enable allowJs in the typescript tscconfig, you can compile both javascripts and typescripts in tsc, so I feel like I can do almost the same thing for laymen.

I think I can do it with tsc because I have some problems, but I couldn't find out.